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NF-H Antibody (RT-97 + NR-4) - IHC-Prediluted, Novus Biologicals™

Product Code. 18181888 Shop All Bio Techne Products
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7 mL
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7mL
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Product Code. 18181888 Supplier Novus Biologicals Supplier No. NBP248253

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Mouse Monoclonal Antibody

NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Chicken samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NF-H
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone RT-97 + NR-4
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Gene Symbols NEFH
Host Species Mouse
Immunogen Triton-X 100 insoluble proteins of rat brain (RT-97); Neurofilaments from porcine spinal cord (NR-4) (Uniprot: P12036)
Purification Method Protein G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 4744
Test Specificity This monoclonal antibody reacts with a 200kDa and 68kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Target Species Human, Mouse, Rat, Pig, Chicken
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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