NKG2A/C/E Rat anti-Mouse, FITC, Clone: 20d5, eBioscience™
Rat Monoclonal Antibody
Merk: Affymetrix eBioscience 11-5896-85
Overige gegevens : Gewicht : 0.25000kg
BeschrijvingNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Klrc1, Klrc2, Klrc3|
|4° C, store in dark, DO NOT FREEZE!|
|16641, 16642, 58179|
|CD159A, NKG2, NKG2A, C-lectin type II protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-1/B activating NK receptor, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, natural killer cell l, KLRC1, cd159e, cd159c|
For Research Use Only.