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NKG2D/CD314 Antibody (1D11), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NB100-65956G

Product Code. 18218920

  • € 628.00 / 0.25mL

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Description

Description

NKG2D/CD314 Monoclonal specifically detects NKG2D/CD314 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NKG2D/CD314
Monoclonal
DyLight 488
P26718
KLRK1
NKL cells.
0.25 mL
Primary
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Store at 4C in the dark.
IgG1
Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
1D11
Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Mouse
Protein G purified
RUO
22914
Human
Purified
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