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Invitrogen™ NKp30 Polyclonal Antibody

Description
Immunogen sequence: MAWMLLLILI MVHPGSCALW VSQPPEIRTL EGSSAFLPCS FNASQGRLAI GSVTWFRDEV VPGKEVRNGT PEFRGRLAPL ASSRFLHDHQ AELHIRDVRG; Positive Samples: K-562, Raji, HP-1, H460, Mouse spleen, Mouse thymus, Mouse lung, Rat thymus; Cellular Location: Cell membrane, Single-pass type I membrane protein.
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].
Specifications
Specifications
| Antigen | NKp30 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.62 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | Ncr3 |
| Gene Accession No. | O14931 |
| Gene Alias | 1C7; Activating natural killer receptor p30; activating NK-A1 receptor; CD337; LY117; lymphocyte antigen 117; MALS; Natural cytotoxicity triggering receptor 3; natural killer cell p30-related protein; natural killer cell receptor; Ncr3; NK receptor 1c7; Nkp30; NK-p30; NKp30S; NKp30v1; NKp30v1ED |
| Gene Symbols | Ncr3 |
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