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Invitrogen™ NMDAR1 Polyclonal Antibody
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Product Code. 11568751
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Quantity:
200 μL
Unit Size:
200µL
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11568751 200 μL 200µL
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Product Code. 11568751 Supplier Invitrogen™ Supplier No. PA3102

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Description

Rabbit Polyclonal Antibody

PA3-102 detects N-methyl-D-aspartate (NMDA) receptor type 1. PA3-102 has been used successfully in Western blot, ELISA, immunoprecipitation, immunohistochemistry, and immunocytochemistry procedures. In Western blot analysis of rat brain synaptic membranes this antibody detects a ~120 kDa protein representing NMDA receptor type 1. The PA3-102 immunogen is a synthetic peptide corresponding to residues (195)N Y E N L D Q L S Y D N K R G P(210) C of Exon 5 of rat NMDA Receptor Type 1 (Isoforms B, F, G).

NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NMDAR1
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene GRIN1
Gene Accession No. P35438, P35439, Q05586
Gene Alias GluN1; Glun1r; GluRdelta1; Glurz1; GluRzeta1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; glutamate ionotropic receptor NMDA type subunit 1; glutamate receptor; glutamate receptor ionotropic, NMDA 1; glutamate receptor subunit zeta 1; glutamate receptor, ionotropic, NMDA1 (zeta 1); glutamate receptor, ionotropic, N-methyl D-aspartate 1; GRIN1; M100174; MRD8; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDA receptor 1; NMDA1; Nmdar; NMDAR1; NMD-R1; NMDZ1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor 1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMZ1; NR1; NR1C1; NR1C2; NR1C2'; NR1N1; pGluN1; Rgsc174; RP11-350O14.1
Gene Symbols GRIN1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues (195)N Y E N L D Q L S Y D N K R G P(210) C of Exon 5 of rat NMDA Receptor Type 1 (Isoforms B, F, G).
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14810, 24408, 2902
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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