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Invitrogen™ NME4 Polyclonal Antibody

Product Code. 16549851
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Quantity:
100 μL
Unit Size:
100µL
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16549851 100 μL 100µL
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Product Code. 16549851 Supplier Invitrogen™ Supplier No. PA597017

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MGGLFWRSAL RGLRCGPRAP GPSLLVRHGS GGPSWTRERT LVAVKPDGVQ RRLVGDVIQR FERRGFTLVG MKMLQAPESV LAEHYQDLRR KPFYPALIRY MSSGPVVAMV WEGYNVVRAS RAMIGHTDSA EAAPGTIRGD FSVHISRNVI HASDSVEGAQ REIQLWFQSS ELVSWADGGQ HSSIHPA; Positive Samples: Jurkat, A-549, NCI-H460, BT-474, Mouse kidney, Mouse stomach, Rat brain; Cellular Location: Mitochondrion intermembrane space, Mitochondrion matrix, Peripheral membrane protein.

NME4 is a protein kinases, which are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
TRUSTED_SUSTAINABILITY

Specifications

Antigen NME4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NME4
Gene Accession No. O00746, Q9WV84
Gene Alias 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; expressed in non-metastatic cells 4, protein; NDK; NDP kinase D; NDP kinase, mitochondrial; NDPKD; NDPK-D; NM23D; NM23H4; nm23-H4; Nm23M4; NM23-M4; NM23-Z4; NME/NM23 nucleoside diphosphate kinase 4; Nme4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial; Unknown (protein for MGC:134183); zgc:56482
Gene Symbols NME4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human NME4 (NP_0050001).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4833, 56520, 685679
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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