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Invitrogen™ NOLA1 Polyclonal Antibody
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Product Code. 15701432 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15701432 100 μL 100µL
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Product Code. 15701432 Supplier Invitrogen™ Supplier No. PA563656

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GRGGFNKGQD QGPPERVVLL GEFLHPCEDD IVCKCTT Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Required for ribosome biogenesis and telomere maintenance. NOLA1 is part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. NOLA1 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOLA1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GAR1
Gene Accession No. Q9NY12
Gene Alias AA409823; AI326794; C430047J18Rik; Gar1; GAR1 homolog, ribonucleoprotein; GAR1 ribonucleoprotein; GAR1 ribonucleoprotein homolog; GAR1 ribonucleoprotein homolog (yeast); H/ACA ribonucleoprotein complex subunit 1; H/ACA small nucleolar RNPs; Nola1; Nucleolar protein family A member 1; nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs); snoRNP protein GAR1
Gene Symbols GAR1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NOLA1. Recombinant protein control fragment (Product #RP-101734).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54433
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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