missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ NOTCH3 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142191
This item is not returnable.
View return policy
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Specifications
| NOTCH3 | |
| Polyclonal | |
| Unconjugated | |
| Notch3 | |
| AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 4854 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9UM47 | |
| Notch3 | |
| Peptide with sequence C-QLGPQPEVTPKRQ. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Haben Sie Verbesserungsvorschläge?Übermitteln Sie eine inhaltliche Korrektur