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Invitrogen™ NOTCH3 Recombinant Rabbit Monoclonal Antibody (1A7L4)

Rabbit Recombinant Monoclonal Antibody

€ 176.00 - € 436.00

Specifications

Antigen NOTCH3
Clone 1A7L4
Concentration 1.32 mg/mL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Applications ELISA, Western Blot
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30283379
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Invitrogen™
MA557979
20 μL
€ 176.00
20µL
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30283105
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Invitrogen™
MA557980
100 μL
€ 436.00
100µL
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Description

Description

Immunogen sequence: PAAGAHSSPP KARFLRVPSE HPYLTPSPES PEHWASPSPP SLSDWSESTP SPATATGAMA TTTGALPAQP LPLSVPSSLA QAQTQLGPQP EVTPKRQVLA.

NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Specifications

Specifications

NOTCH3
1.32 mg/mL
ELISA, Western Blot
Unconjugated
Rabbit
RUO
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Q9UM47
4854
A synthetic peptide corresponding to a sequence within amino acids 2222-2321 of human NOTCH3 (NP_000426.2).
Antibody
1A7L4
-20°C, Avoid Freeze/Thaw Cycles
Recombinant Monoclonal
Liquid
IgG
Human
Notch3
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
Notch3
Primary
Protein A
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