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Invitrogen™ NOTCH4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5115664
This item is not returnable.
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Description
Antibody detects endogenous levels of total NOTCH4.
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases (entrez gene).
Specifications
| NOTCH4 | |
| Polyclonal | |
| Unconjugated | |
| NOTCH4 | |
| DAQB-143M3.4; FLJ16302; hNotch4; Int3; Int-3; MGC74442; N4; neurogenic locus notch homolog protein 4; Notch 4; Notch 4 extracellular truncation; Notch 4 intracellular domain; Notch gene homolog 4; Notch homolog 4; notch receptor 4; NOTCH3; Notch4; putative Notch4 protein; Transforming protein Int-3 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 18132, 406162, 4855 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide | |
| P31695, Q99466 | |
| NOTCH4 | |
| A synthesized peptide derived from human NOTCH4(Accession Q99466), corresponding to amino acid residues R1474-G1524. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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