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Beskrivning
Immunogen sequence: NLNTLGLGLS QAAATGALAA AAASANPAAA AANLLATYAS EASASGSTAG GTAGTFALGS LAAATAATNG YFGAASPLAA SAILGTEKST DGSKDVVEIA VPENLVGAIL GKGGKTLVEY QELTGARI Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Specifikationer
Specifikationer
| Antigen | NOVA1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | NOVA1 |
| Gene Accession No. | P51513 |
| Gene Alias | 9430099M15Rik; G630039L02; neuro-oncological ventral antigen 1; NOVA alternative splicing regulator 1; Nova1; Nova-1; Onconeural ventral antigen 1; paraneoplastic Ri antigen; RNA-binding protein Nova-1; ventral neuron-specific protein 1 |
| Gene Symbols | NOVA1 |
| Visa mer |
Produkttitel
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