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Invitrogen™ NPC1 Recombinant Rabbit Monoclonal Antibody (24GB620)
Rabbit Recombinant Monoclonal Antibody
€ 146.00 - € 500.00
Specifications
| Antigen | NPC1 |
|---|---|
| Clone | 24GB620 |
| Concentration | 0.85 mg/mL |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30276517
|
Invitrogen™
MA557129 |
100 μL |
€ 500.00
100µL |
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|
30276061
|
Invitrogen™
MA557130 |
20 μL |
€ 146.00
20µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
NPC1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids. The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolyzed and released as free cholesterol. NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations.Specifications
| NPC1 | |
| 0.85 mg/mL | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O15118, O35604 | |
| 18145, 266732, 4864 | |
| A synthesized peptide derived from human Niemann Pick C1 (aa 1240-1278). | |
| Antibody |
| 24GB620 | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| NPC1 | |
| A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1 | |
| NPC1 | |
| Primary | |
| Affinity chromatography |
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