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Invitrogen™ NPHP3 Polyclonal Antibody
Description
Immunogen sequence: MGTASSLVSP AGGEVIEDTY GAGGGEACEI PVEVKPKARL LRNSFRRGAG AAAGAGPGSL PRGVGAGGLL GASFKSTGSS VPELEYAAAE YERLRKEYEI FRVSKNQELL SMGRREAKLD TENKRLRAEL; Positive Samples: 293T, Mouse liver; Cellular Location: Cell projection, cilium.
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
Specifications
Specifications
| Antigen | NPHP3 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.54 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | NPHP3 |
| Gene Accession No. | Q7TNH6, Q7Z494 |
| Gene Alias | 3632410F03Rik; AI550417; C230078J01; CFAP31; cilia and flagella associated protein 31; D330020E01Rik; Kiaa2000; Meckel syndrome, type 7; MKS7; Nephrocystin-3; nephronophthisis 3 (adolescent); NPH3; NPHP3; pcy; RHPD; RHPD1; SLSN3 |
| Gene Symbols | NPHP3 |
| Show More |
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