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Invitrogen™ NR5A1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5139965
This item is not returnable.
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Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: VPELILQLLQ LEPDEDQVRA RILGCLQEPT KSRPDQPAAF GLLCRMADQT Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 90%.
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 has been shown to be essential for fetal development of the hypothalamus, pituitary gland, gonads, and the adrenal gland. SF-1 has been shown to promote transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains, designated AF1 and AF2, common to many nuclear steroid receptors which have been shown to be necessary for interaction with other nuclear receptors as well as coactivators and corepressors including steroid receptor coactivator-1 (SRC-1), glucocorticoid receptor interacting protein 1 (GRIP1), cAMP response element binding protein (CREB) binding protein (CBP) and silencing mediator of retinoid acid and thyroid hormone receptor (SMRT).
Specifications
| NR5A1 | |
| Polyclonal | |
| Unconjugated | |
| Nr5a1 | |
| Ad4BP; Ad4BP/SF-1; adrenal 4 binding protein; Adrenal 4 binding protein (AD4BP); adrenal 4-binding protein; ELP; ELP-3; Embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; FTZ1; FTZF1; Ftz-F1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; Fushi tarazu factor homolog 1 (FTZ1); hSF-1; Nr5a1; nuclear receptor AdBP4; nuclear receptor subfamily 5 group A member 1; Nuclear receptor subfamily 5 group A member 1 (NR5A1); nuclear receptor subfamily 5, group A, member 1; POF7; SF1; SF-1; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; Steroidogenic factor 1; Steroidogenic factor 1 (SF1); steroidogenic factor 1 nuclear receptor; steroidogenic factor-1; STF1; STF-1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2516 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q13285 | |
| Nr5a1 | |
| Recombinant protein corresponding to Human NR5A1. Recombinant protein control fragment (Product #RP-109691). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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