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Invitrogen™ NR5A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA5110041

Product Code. 17137973

€ 493.00 / 100µL

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Description

Immunogen sequence: SIPHLILELL KCEPDEPQVQ AKIMAYLQQE QANRSKHEKL STFGLMCKMA DQTLFSIVEW ARSSIFFREL KVDDQMKLLQ NCWSELLILD HIYRQVVHGK EGSIFLVTGQ QVDYSIIASQ AGATLNNLMS HAQELVAKLR SLQFDQREFV CLKFLVLFSL DVKNLENFQL VEGVQEQVNA ALLDYTMCNY PQQTEKFGQL LLRLPEIRAI SMQAEEYLYY KHLNGDVPYN NLLIEMLHAK RA.

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Specifications

Antigen	NR5A2
Classification	Polyclonal
Conjugate	Unconjugated
Gene	Nr5a2
Gene Alias	Alpha-1-fetoprotein transcription factor; AU020803; B1-binding factor; b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; B1F; B1F2; CPF; CYP7A promoter-binding factor; D1Ertd308e; fetoprotein transcription factor; fetoprotein-alpha 1 (AFP) transcription factor; Ftf; FTF/LRH-1; FTZ F1; FTZ F1beta; FTZ-F1; FTZ-F1 beta; FTZ-F1 beta2 protein; FTZ-F1beta; hB1F; hB1F 2; hB1F-2; Hepatocytic transcription factor; hepatocytic transcription factor hB1F-3; I79_021747; live; liver nuclear receptor homolog-1 variant 2; liver receptor homolog 1; liver receptor homolog-1; Lrh1; LRH-1; Nr5a2; Nuclear receptor subfamily 5 group A member 2; nuclear receptor subfamily 5, group A, member 2; OR2.0; orphan nuclear receptor; SF-2; steroidogenic factor 2; UF2-H3B
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	2494, 26424, 60349
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Concentration	1.81 mg/mL
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.	O00482, P45448, Q9QWM1
Gene Symbols	Nr5a2
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 300-541 of human NR5A2 (NP_9955821).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse, Rat
Product Type	Antibody
Isotype	IgG

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Invitrogen™ NR5A2 Polyclonal Antibody

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