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Tocris Bioscience™ NS 3728
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Product Code. 18747046
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Product Code. 18747046 Supplier Tocris Bioscience™ Supplier No. 6973/50

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Description

VRAC blocker

NS 3728 is a volume-regulated anion channel (VRAC) blocker (IC50 = 460 nM). Blocks red blood cell chloride conductance (IC50 = 0.6 μM). NS 3728 also inhibits Ca2+-activated Cl- current (CaCC) by anoctamin (ANO) in an apparently voltage-dependent manner (IC50 against ANO1 = 2.1 and 0.7 μM at -95 and +50 mV, respectively).
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Specifications

Chemical Name or Material N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea
CAS 265646-85-3
Quantity 50 mg
Target Other Chloride Channel Blockers
Molecular Formula C16H9BrF6N6O
Purity 0.98
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