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Invitrogen™ NTAL Polyclonal Antibody

Product Code. 16319064
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Quantity:
100 μL
Unit Size:
100µL
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16319064 100 μL 100µL
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Product Code. 16319064 Supplier Invitrogen™ Supplier No. PA582095

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AKRSEKIYQQ RSLREDQQSF TGSRTYSLVG QAWPGPLADM APTRKDKLLQ FYPSLEDPAS SRYQNFSKGS RHGSEEAYID PIAMEYYNWG RFSKPPEDDD ANSYENVLIC KQKTTETGAQ QEGIGGLCRG DLSLSLALKT GPT Highest antigen sequence indentity to the following orthologs: Rat - 46%, Mouse - 46%.

NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTAL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LAT2
Gene Accession No. Q9GZY6
Gene Alias AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Gene Symbols LAT2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LAT2. Recombinant protein control fragment (Product #RP-102142).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7462
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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