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NUMB Monoclonal Antibody (OTI1A12), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA802316
This item is not returnable.
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Description
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.Specifications
| NUMB | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P49757 | |
| NUMB | |
| Human recombit protein fragment corresponding to amino acids 1-365 of human NUMB produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Western Blot | |
| OTI1A12 | |
| Unconjugated | |
| NUMB | |
| C14orf41, S171, c14_5527 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 8650 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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