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Invitrogen™ NUP35 Polyclonal Antibody

Description
Immunogen sequence: MAAFAVEPQG PALGSEPMML GSPTSPKPGV NAQFLPGFLM GDLPAPVTPQ PRSISGPSVG VMEMRSPLLA GGSPPQ Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 93%.
Nucleoporin Nup35 or Mitotic phosphoprotein 44 is a nuclear protein known to be present on nuclear pore complex and is tightly associated with the nuclear membrane and lamina. This RNA associated protein belongs to the Nup53 family and has a MPPN (mitotic phosphoprotein N' end) domain. It has a small number of scattered phenylalanine-glycine repeats, but not the large domains seen in other nucleoporins. Though the exact function of NUP35 is yet to be revealed, it may function as a component of the nuclear pore complex (NPC) which are collectively referred to as nucleoporins (NUPs). It also may play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors, and may also play an important part in the association of MAD1, a transcriptional repressor with the NPC. NUP35 is widely expressed in most of the tissues.
Specifications
Specifications
| Antigen | NUP35 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | NUP35 |
| Gene Accession No. | Q8NFH5 |
| Gene Alias | 2310006I24Rik; 35 kDa nucleoporin; 35kDa; 5330402E05Rik; Mitotic phosphoprotein 44; Mp44; MP-44; NO44; NP44; Nuclear pore complex protein Nup53; nucleoporin 35; nucleoporin 35kDa; nucleoporin NUP35; Nucleoporin NUP53; Nup35; NUP53 |
| Gene Symbols | NUP35 |
| Show More |
Product Title
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