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Invitrogen™ NXPH2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5103960
This item is not returnable.
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Description
Antibody detects endogenous levels of total NXPH2.
Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I-alpha (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.
Specifications
| NXPH2 | |
| Polyclonal | |
| Unconjugated | |
| NXPH2 | |
| neurexophilin 2; Neurexophilin2; neurexophilin-2; NPH2; Nxph2 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 11249, 18232 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O95156, Q61199 | |
| NXPH2 | |
| A synthesized peptide derived from human NXPH2(Accession O95156), corresponding to amino acid residues F169-H219. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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