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Invitrogen™ OAS2 Polyclonal Antibody

Description
Immunogen sequence: TQYQQLCIFW KVNYNFEDET VRKFLLSQLQ KTRPVILDPA EPTGDVGGGD RWCWHLLAKE AKEWLSSPCF KDGTGNPIPP WKVPTMQTPG SCGARIHPIV N.
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications
Specifications
| Antigen | OAS2 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 3.96 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | OAS2 |
| Gene Accession No. | P29728 |
| Gene Alias | (2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; 2',5'-oligoadenylate synthetase-like 11; 2,5-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase 2; 2'-5' oligoadenylate synthetase-like 11; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; A synthetase 2; MGC78578; Oas2; Oasl11; p69 OAS / p71 OAS; p69OAS / p71OAS |
| Gene Symbols | OAS2 |
| Show More |
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