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Invitrogen™ OAS3 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597217

Product Code. 16530052

  • € 528.00 / 100µL

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Description

Description

Immunogen sequence: AASCYDHPCF LRGMGDPVQS WKGPGLPRAG CSGLGHPIQL DPNQKTPENS KSLNAVYPRA GSKPPSCPAP GPTGAASIVP SVPGMALDLS QIPTKELDRF IQDHLKPSPQ FQEQVKKAID IILRCLHENC VHKASRVSKG GSFGRGTDLR DGCDVELIIF LNCFTDYKDQ GPRRAEILDE MRAQLESWWQ DQVPSLSLQF PEQNVPEALQ FQLVSTALKS WTDVSLLPAF DAVGQLSSGT KPNPQVYSRL LTSGCQEGEH KACFAELRRN FMNIRPVKLK NLILLVKHWY RQVAAQNKGK G; Positive Samples: U-87MG, DU145, HeLa; Cellular Location: Cytoplasm, Nucleus.

OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

OAS3
Polyclonal
Unconjugated
OAS3
(2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2',5'-oligoadenylate synthetase-like 10; 2'-5' oligoadenylate synthetase 3; 2'-5' oligoadenylate synthetase-like 10; 2-5A synthase 3; 2-5A synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; Oas3; oasl10; P/OKcl.4; p100; p100 OAS; p100OAS
Rabbit
Affinity Chromatography
RUO
246727, 4940, 494202
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.62 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Q5MYT7, Q8VI93, Q9Y6K5
OAS3
Recombinant protein (or fragment)
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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