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Invitrogen™ OATP1 Polyclonal Antibody

Product Code. 15929824
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
15929824 100 μL 100µL
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Product Code. 15929824 Supplier Invitrogen™ Supplier No. PA567149

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FLPNTLPKEGL ETNADIIKNE NEDKQKEEVK KEKYGITKDF LPFMKSLSCN Highest antigen sequence identity to the following orthologs - mouse 65%, rat 63%.

The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OATP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLCO1A2
Gene Accession No. P46721
Gene Alias A530084B21; Brain digoxin carrier protein; brain-specific organic anion transporter; membrane transporter; OATP; Oatp1; OATP-1; Oatp1a1; OATP1A2; Oatp1a4; Oatp2; OATPA; OATP-A; OATP-B1; organic anion transporter 2; organic anion transporting polypeptide 1; organic anion transporting polypeptide 1a2; organic anion transporting polypeptide 1a2 variant 1; organic anion transporting polypeptide A; organic anion-transporting polypeptide 1; Slc21a1; SLC21A3; Slc21a5; Slco1a1; SLCO1A2; Slco1a4; SO1A2; Sodium-independent organic anion transporter; sodium-independent organic anion transporter 1; Sodium-independent organic anion-transporting polypeptide 1; sodium-independent organic anion-transporting polypeptide 2; solute carrier family (organic anion transporter) member 1; solute carrier family (organic anion transporter) member 3; solute carrier family 21 (organic anion transporter), member 1; solute carrier family 21 (organic anion transporter), member 3; solute carrier family 21 (organic anion transporter), member 5; solute carrier family 21 member 1; Solute carrier family 21 member 3; solute carrier family 21 member 5; solute carrier family 21, member 1; solute carrier organic anion transporter family member 1A1; Solute carrier organic anion transporter family member 1A2; solute carrier organic anion transporter family member 1A4; solute carrier organic anion transporter family, member 1a1; solute carrier organic anion transporter family, member 1A2; solute carrier organic anion transporter family, member 1a4
Gene Symbols SLCO1A2
Host Species Rabbit
Immunogen Recombinant Human OATP1. Recombinant protein control fragment (Product #RP-105520).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6579
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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