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OBFC2B Monoclonal Antibody (OTI1E11), TrueMAB™, OriGene

Product Code. 17530602
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100 μL
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17530602 100 μL 100µL
17550602 30 μL 30µL
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Product Code. 17530602 Supplier Origene Technologies Supplier No. TA504022

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Description

Mouse Monoclonal Antibody

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Specifications

Antigen OBFC2B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1E11
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NABP2
Gene Accession No. Q9BQ15
Gene Alias OBFC2B, SOSS-B1, SSB1, hSSB1
Gene Symbols NABP2
Host Species Mouse
Immunogen Full length human recombit protein of human OBFC2B produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79035
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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