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Invitrogen™ OBFC2B Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100654

Product Code. 16677134

  • € 493.00 / 100µL

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Description

Description

Antibody detects endogenous levels of total OBFC2B.

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

OBFC2B
Polyclonal
Unconjugated
NABP2
2610036N15Rik; hSSB1; LP3587; Nabp2; nucleic acid binding protein 2; nucleic acid-binding protein 2; Obfc2b; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; RGD1308158; Sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
Rabbit
Affinity chromatography
RUO
362813, 69917, 79035
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q3SWT1, Q8R2Y9, Q9BQ15
NABP2
A synthesized peptide derived from human NABP2(Accession Q9BQ15), corresponding to amino acid residues P175-R211.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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