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Invitrogen™ ORMDL1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA566786
This item is not returnable.
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Description
Immunogen sequence: FETPDQGKARL LTHWEQLDYG VQFTSSR Highest antigen sequence identity to the following orthologs - mouse 96%, rat 93%.
The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in -gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Specifications
| ORMDL1 | |
| Polyclonal | |
| Unconjugated | |
| ORMDL1 | |
| Adoplin-1; C730042F17Rik; HSPC202; ORM1-like 1; ORM1-like 1 (S. cerevisiae); ORM1-like protein 1; ORMDL sphingolipid biosynthesis regulator 1; ORMDL1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 94101 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9P0S3 | |
| ORMDL1 | |
| Recombinant Human ORMDL1. Recombinant protein control fragment (Product #RP-105362). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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