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Invitrogen™ OSMR Polyclonal Antibody
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Product Code. 15545752
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100 μL
Unit Size:
100µL
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15545752 100 μL 100µL
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Product Code. 15545752 Supplier Invitrogen™ Supplier No. PA542870

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Rabbit Polyclonal Antibody

Peptide sequence: YQSEVLAERL PLTPVSLKVS TNSTRQSLHL QWTVHNLPYH QELKMVFQIQ Sequence homology: Cow: 77%; Dog: 79%; Human: 100%.

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OSMR
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene OSMR
Gene Accession No. Q99650
Gene Alias IL-31 receptor subunit beta; IL-31R subunit beta; IL-31RB; IL-31R-beta; interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin M receptor; oncostatin receptor; oncostatin-M specific receptor beta subunit; oncostatin-M specific receptor subunit beta; oncostatin-M-specific receptor subunit beta; OSMR; Osmrb; PLCA1
Gene Symbols OSMR
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human OSMR (aa 21-70).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9180
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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