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Invitrogen™ OTOF Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA552935
This item is not returnable.
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Description
Immunogen sequence: PIIVIEIYDQ DSMGKADFMG RTFAKPLVKM ADEAYCPPRF PPQLEYYQIY RGNATAGDLL AAFELLQIGP AGKADLPPIN GPVDVDRGPI MPVPMGIRPV LSKYRVEVLF WGLRDLKRVN L Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.
Specifications
| OTOF | |
| Polyclonal | |
| Unconjugated | |
| OTOF | |
| AUNB1; DFNB6; DFNB9; FER1L2; fer-1-like family member 2; fer-1-like protein 2; NSRD9; Otof; Otoferlin | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9381 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9HC10 | |
| OTOF | |
| Recombinant protein corresponding to Human OTOF. Recombinant protein control fragment (Product #RP-90139). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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