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Oxaprozin, MedChemExpress

Product Code. 16458466
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Product Code. 16458466

Brand: Medchem Express HYB0808

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Description

MedChemExpress Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.

Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.

Specifications

Chemical Name or Material Oxaprozin
Physical Form Solid
CAS 21256-18-8
Color White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C18H15NO3
For Use With (Application) COVID-19-immunoregulation
Synonym Oxaprozinum Wy21743
Solubility Information DMSO : ≥ 100 mg/mL (340.92 mM)
SMILES O=C(O)CCC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1
Molecular Weight (g/mol) 293.32
Formula Weight 293.32
Percent Purity 99.76%
Grade Research
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Research purposes only

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