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Invitrogen™ p130Cas Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5143075
This item is not returnable.
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Description
Additional Information: This antibody is expected to recognize reported isoforms1, 2, 3, 5, 6 and 7. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
Specifications
| p130Cas | |
| Polyclonal | |
| Unconjugated | |
| BCAR1 | |
| AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 9564 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P56945 | |
| BCAR1 | |
| Peptide with sequence C-KQTSTFSKQTPHH. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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