missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ p53R2 Recombinant Rabbit Monoclonal Antibody (HL1400)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA547032
This item is not returnable.
View return policy
Description
Store as concentrated solution. Centrifuge briefly prior to opening vial.
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
Specifications
| p53R2 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| Q6PEE3, Q7LG56 | |
| Rrm2b | |
| Recombinant protein encompassing a sequence within the center region of human p53R2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot | |
| HL1400 | |
| Unconjugated | |
| Rrm2b | |
| MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; RRM2B; TP53-inducible ribonucleotide reductase M2 B | |
| Rabbit | |
| Protein A | |
| RUO | |
| 299976, 382985, 50484 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction