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p57Kip2Ab-6 Mouse Monoclonal Antibody, Epredia™
Deliver accurate, reproducible results with the Epredia™ p57Kip2 Ab-6, Mouse Monoclonal Antibody.
€ 154.00 - € 1055.00
Specifications
| Antigen | p57superscriptKip2superscript Ab-6 |
|---|---|
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Product Code | Brand | Form | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Form | Quantity | Price | Quantity & Availability | ||||
|
12668776
|
Epredia
MS-1062-P0 |
Concentrated | 100 μL |
€ 154.00
100µL |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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|
12678776
|
Epredia
MS-1062-P1 |
Concentrated | 500 μL |
€ 449.00
500µL |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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|
12658776
|
Epredia
MS-1062-P |
Concentrated | 1 mL |
€ 1055.00
1mL |
Estimated Shipment: 10-06-2024 Log in to see stock. |
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|
12628786
|
Epredia
MS-1062-R7 |
Prediluted | 7 mL |
€ 423.00
7mL |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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|
12698776
|
Epredia
MS-1062-PABX |
Concentrated | 200 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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|
12688776
|
Epredia
MS-1062-P1ABX |
Concentrated | 100 μL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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|
12638786
|
Epredia
MS-1062-RQ |
Ready-to-Use | 12 mL |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
p57Kip2 (or CDKN1C) is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. The gene encoding human p57Kip2 is located on chromosome 11p15.5, a region implicated in both sporadic cancers, Wilm's tumor, and Beckwith-Wiedemann syndrome (BWS), a cancer syndrome, making it a tumor suppressor candidate. BWS is characterized by numerous growth abnormalities and an increased risk of childhood tumors. Several types of childhood tumors including Wilms' tumor, adrenocortical carcinoma and rhabdomyosarcoma display a specific loss of maternal 11p15 alleles, suggesting that genomic imprinting plays an important part. This region also contains two other imprinted genes, insulin-like growth factor II (IGF-II) and H19, both of which seem to be implicated in adrenal neoplasms.Host Species: Mouse
Clone: 57P06; same as KP10
Isotype: IgG2b/κ
Species Reactivity: Human and Mouse. Others not known.
Epitope: Not determined
Immunogen: Recombinant human p57Kip2 protein
Molecular Weight: 57kDa
Positive Control: LS174T cells, Colon CA or placenta
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not suitable)
- Immunoprecipitation (Native verified)
Specifications
| p57superscriptKip2superscript Ab-6 | |
| Monoclonal | |
| Mouse | |
| Cell Cycle | |
| Primary |
| Immunohistochemistry (Paraffin), Immunoprecipitation | |
| Unconjugated | |
| IVD | |
| Recombinant human p57superscriptKip2superscript protein |