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p73 Antibody (5B429), DyLight 350, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-24737UV

Product Code. 18197591

  • € 605.00 / 0.10mL

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Description

Description

p73 Monoclonal specifically detects p73 in Human, Mouse, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

p73
Monoclonal
DyLight 350
O15350
TP73
This antibody was raised against full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
0.1 mL
Apoptosis, Cancer, Tumor Suppressors
7161
Human, Mouse, Rat
Purified
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
5B429
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
p53-related protein, P73p53-like transcription factor, TA p73, TAp73, tumor protein p73
Mouse
Protein G purified
RUO
Primary
p73 antibody (clone 5B429) recognizes all of the TAp73 isoforms i.e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 IMG-246/ NBP2-24737 reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 (NB100-56674/ IMG-259A ) showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kDa and 45 kDa, have been described in literature (Sayan et al, 2008).
Store at 4C in the dark.
IgG1 κ
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