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PACSIN2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA596804
This item is not returnable.
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Description
Immunogen sequence: RLRFFREVLL EVQKHLDLSN VAGYKAIYHD LEQSIRAADA VEDLRWFRAN HGPGMAMNWP QFEEWSADLN RTLSRREKKK ATDGVTLTGI NQTGDQSLPS KPSSTLNVPS NPAQSAQSQS SYNPFEDEDD TGSTVSEKDD TKAKNVSSYE KTQSYPTDWS DDESNNPFSS T; Positive Samples: BT-474, HepG2, Mouse lung, Mouse heart; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
Specifications
| PACSIN2 | |
| Polyclonal | |
| Unconjugated | |
| PACSIN2 | |
| AI197433, cytoplasmic phosphoprotein PACSIN2, Pacsin2, pacsin2.S, protein kinase C and casein kinase substrate in neurons 2, protein kinase C and casein kinase substrate in neurons 2 protein, protein kinase C and casein kinase substrate in neurons 2 S homeolog, protein kinase C and casein kinase substrate in neurons protein 2, RP3-437M21.1, SdpII, SdpIIsyndapin II, synaptic dynamin-associated protein II, syndapin 2, Syndapin II, syndapin2, syndapin-2, Syndapin-II, XELAEV_18019736mg, x-PACSIN2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 11252, 23970 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.79 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide, pH 7.3 | |
| Q9UNF0, Q9WVE8 | |
| PACSIN2 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PACSIN2 (NP_0091602) | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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