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PADI2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12110-1-AP-20UL

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Product Code. 16819633

  • € 145.00 / 20µL

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Description

Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Specifications

Specifications

PADI2
Polyclonal
Unconjugated
PADI2
KIAA0994, PAD H19, PAD2, PADI2, PDI2, Peptidylarginine deiminase II
Rabbit
Antigen Affinity Chromatography
RUO
11240, 18600, 29511
-20°C
Liquid
Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
0.22 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P20717, Q08642, Q9Y2J8
Padi2
PADI2 Fusion Protein Ag2755
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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