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Invitrogen™ PAM Polyclonal Antibody
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Product Code. 17288383 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17288383 100 μL 100µL
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Product Code. 17288383 Supplier Invitrogen™ Supplier No. PA5115606

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MYCBP2.

This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAM
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene MYCBP2
Gene Accession No. O75592, Q7TPH6
Gene Alias AU023734; AW107953; AW546647; C130061D10Rik; E3 ubiquitin-protein ligase MYCBP2; Highwire; KIAA0916; MYC binding protein 2; MYC binding protein 2, E3 ubiquitin protein ligase; Myc-binding protein 2; Mycbp2; Myc-bp2; PAM; pam, highwire, rpm 1; pam/highwire/rpm-1 protein; Phr; Phr1; probable E3 ubiquitin-protein ligase MYCBP2; protein associated with Myc; Protein Magellan; R75243
Gene Symbols MYCBP2
Host Species Rabbit
Immunogen A synthesized peptide derived from human MYCBP2(Accession O75592), corresponding to amino acid residues S979-E1029.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 105689, 23077, 290447
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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