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Invitrogen™ Pannexin 1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA578455
This item is not returnable.
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Description
Positive Control: U2OS Predicted Reactivity: Rat (81%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Specifications
| Pannexin 1 | |
| Polyclonal | |
| Unconjugated | |
| PANX1 | |
| AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 24145 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.26 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q96RD7 | |
| PANX1 | |
| Recombinant protein encompassing a sequence within the Intracellular domain of human Pannexin 1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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