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  6. Invitrogen™ Parkin Chimeric Recombinant Mouse Monoclonal Antibody (21H24L9), Invitrogen™

Invitrogen™ Parkin Chimeric Recombinant Mouse Monoclonal Antibody (21H24L9), Invitrogen™

Product Code. 30130944
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Quantity:
20 μL
100 μL
Unit Size:
100µg
20µL
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Product Code. Quantity unitSize
30130944 20 μL 20µL
30131442 100 μL 100µg
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Product Code. 30130944 Supplier Invitrogen™ Supplier No. 702785M20UG

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Description

Mouse Recombinant Monoclonal Antibody

This antibody has Rabbit Variable heavy and light chains, and Mouse constant domains. It recognizes human, mouse and Rat Parkin protein. This chimeric antibody is recognized by anti-mouse secondary antibodies and has no cross reactivity to anti-rabbit secondary antibodies. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Parkin Chimeric
Applications Western Blot
Classification Recombinant Monoclonal
Clone 21H24L9
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PRKN
Gene Accession No. O60260, Q9JK66, Q9WVS6
Gene Alias AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel\CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679
Gene Symbols PRKN
Host Species Mouse
Immunogen Protein corresponding to human Parkin [aa1-aa465].
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5071, 50873, 56816
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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