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Invitrogen™ PARL Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA542653
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Description
Peptide sequence: SLIKPLFFTV GFTGCAFGSA AIWQYESLKS RVQSYFDGIK ADWLDSIRPQ Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%.
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications
| PARL | |
| Polyclonal | |
| Unconjugated | |
| PARL | |
| D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300} | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 55486 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q9H300 | |
| PARL | |
| Synthetic peptide directed towards the N-terminal of human PARL (aa 97-146). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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