missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Paromomycin sulfate

Paromomycin sulfate

Product Code. 15413889
Click to view available options
Quantity:
5 g
Unit Size:
5g
This item is not returnable. View return policy

Product Code. 15413889

Brand: Thermo Scientific Alfa Aesar J61274.06

Request Bulk or Custom Format

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Inhibits initiation and elongation during protein synthesis | CAS: 1263-89-4 | C23H47N5O18S | 713.706 g/mol

Paromomycin sulfate salt has been used as a reference compound in antileishmanial activity, RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex. It has also been used in cell culture applications at 100mg/L. Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Paromomycin sulfate salt has been used as a reference compound in antileishmanial activity, RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer to RNA duplex. It has also been used in cell culture applications at 100mg/L. Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

Solubility
Soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1263-89-4
Molecular Formula C23H47N5O18S
Molecular Weight (g/mol) 713.706
MDL Number MFCD00079278
InChI Key LJRDOKAZOAKLDU-JXDXLELXSA-N
PubChem CID 91972180
IUPAC Name (3S,5S,6S)-5-amino-2-(aminomethyl)-6-[(2R,4S,5S)-5-[(2R,5R,6R)-3,5-diamino-2-[(2S,3S,5S)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric acid
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O

Specifications

Type Paromomycin Sulfate
Physical Form Powder
Color White
Quantity 5 g
Optical Rotation +51° (c=5 in Water)
Beilstein 5715182
Merck Index 14,7041
Solubility Information Soluble in water
Formula Weight 713.71
Chemical Name or Material Paromomycin sulfate

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Paromomycin sulphate
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 1A
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H360-May damage fertility or the unborn child.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : Paromomycin sulphates
SDS

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.