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Invitrogen™ Parvalbumin Polyclonal Antibody, Biotin
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142152
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
Specifications
| Parvalbumin | |
| Polyclonal | |
| Biotin | |
| Pvalb | |
| D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 25269, 5816 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P02625, P20472 | |
| Pvalb | |
| Peptide with sequence C-GVDEFSTLVAES (aa 99-110). | |
| 100 μg | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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