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  6. Patched1 Monoclonal Antibody (OTI6C10), TrueMAB™, OriGene

Patched1 Monoclonal Antibody (OTI6C10), TrueMAB™, OriGene

Product Code. 17563233
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100 μL
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30µL
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17563233 100 μL 100µL
17583233 30 μL 30µL
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Product Code. 17563233 Supplier Origene Technologies Supplier No. TA803949

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Description

Mouse Monoclonal Antibody

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.

Specifications

Antigen Patched1
Applications Western Blot
Classification Monoclonal
Clone OTI6C10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene PTCH1
Gene Accession No. Q13635
Gene Alias BCNS, NBCCS, PTC, PTC1, PTCH
Gene Symbols PTCH1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 770-1027 of human PTCH1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5727
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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