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DiscoverX PathHunter™ CHO-K1 GPR26 β-Arrestin Orphan GPCR Cell Line

Product Code. 17383099
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17383099

Brand: DiscoverX 930392C2A

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This item is not returnable. View return policy

Description

The PathHunter™ CHO-K1 GPR26 β-Arrestin Orphan GPCR Cell Line measures GPR26 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ GPR26 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR26 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged GPR26 and EA-tagged β-Arrestin 2. Activation of GPR26 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Orphan receptor with unknown ligand.

Specifications

Assay Entry β-Arrestin recruitment
Cell Line CHO-K1
For Use With (Application) Cell Lines
Quantity 2 Vials
Target Entry GPR26
Accession Number NM_153442
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