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DiscoverX PathHunter™ eXpress ADRA2B CHO-K1 β-Arrestin GPCR Assay

Product Code. 17383579
Encompass
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17383579

Brand: DiscoverX 930641E2CP2L

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This item is not returnable. View return policy

Description

The PathHunter™ eXpress ADRA2B CHO-K1 β-Arrestin GPCR Assay measures ADRA2B (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ ADRA2B β-Arrestin eXpress Kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. epinephrine and norepinephrine) based activation of ADRA2B GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged ADRA2B and EA-tagged β-Arrestin 2. Activation of ADRA2B stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry GPCR
For Use With (Application) Assay-Ready eXpress Kits
Quantity 1,000 dp (10 x 96-well)
Target Entry ADRA2B
Cell Line CHO-K1
Target ADRA2B
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