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DiscoverX PathHunter™ U2OS MCHR1 Bioassay Kit

Product Code. 17394049
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17394049

Brand: DiscoverX 930940Y300149

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This item is not returnable. View return policy

Description

The PathHunter™ U2OS MCHR1 Bioassay Kit measures MCHR1 activity via detection of SH2 recruitment. Bioassay kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ U2OS MCHR1 Bioassay Kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay asseses ligand (e.g. Recombinant Human PDGF-BB) based on activation of MCHR1 GPCR activity via detection of SH2 Recruitment. The included cell line overexpresses ProLink-tagged MCHR1 and EA-tagged. Activation of MCHR1 stimulates the recruitment of and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.

Specifications

Assay Entry SH2 Recruitment
For Use With (Application) Assay-Ready Bioassay Kits
Quantity 200 dp (2 x 96-well)
Cell Line U2OS
Target MCHR1
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