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Invitrogen™ Paxillin Chimeric Recombinant Mouse Monoclonal Antibody (LD4 sAB)
Mouse Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA547941
This item is not returnable.
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Description
Specificity: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Specifications
| Paxillin Chimeric | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| P49023 | |
| PXN | |
| Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD. | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA, Western Blot, Immunocytochemistry | |
| LD4 sAB | |
| Unconjugated | |
| PXN | |
| adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12 | |
| Mouse | |
| Protein A | |
| RUO | |
| 5829 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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