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Invitrogen™ Paxillin Recombinant Rabbit Monoclonal Antibody (RM256)
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Product Code. 16336464 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16336464 100 μL 100µL
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Product Code. 16336464 Supplier Invitrogen™ Supplier No. MA533075

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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: reacts to human Paxillin. Specificity: may also react to mouse or rat Paxillin, as predicted by immunogen homology. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Paxillin
Applications Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone RM256
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene PXN
Gene Accession No. P49023
Gene Alias adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
Gene Symbols PXN
Host Species Rabbit
Immunogen A peptide corresponding to the N-terminus of human Paxillin.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5829
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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