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Invitrogen™ Paxillin Recombinant Rabbit Monoclonal Antibody (SY23-02)
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Product Code. 16355514
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Quantity:
100 μL
Unit Size:
100µL
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16355514 100 μL 100µL
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Product Code. 16355514 Supplier Invitrogen™ Supplier No. MA532087

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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
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Specifications

Antigen Paxillin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone SY23-02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene PXN
Gene Accession No. P49023, Q66H76, Q8VI36
Gene Alias adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
Gene Symbols PXN
Host Species Rabbit
Immunogen Synthetic peptide within Human Paxillin aa 1-59.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19303, 360820, 5829
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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