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Invitrogen™ PCGF5 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558353

Product Code. 15746231

  • € 566.00 / 100µL

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Description

Description

Immunogen sequence: TCIVQHFEDS NDCPRCGNQV HETNPLEMLR LDNTLEEIIF KLVPGLREQE LERESEFWKK NKPQENGQDD TSKAD Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:26151332). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (PubMed:26151332). Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PCGF5
Polyclonal
Unconjugated
PCGF5
0610009F02Rik; 1110054A01Rik; 5830406C17Rik; 5830443C21Rik; 9530023M17Rik; AI324127; Pcgf5; polycomb group ring finger 5; polycomb group RING finger protein 5; polycomb group RING finger protein 5-like protein; ring finger protein (C3HC4 type) 159; RING finger protein 159; Rnf159
Rabbit
Antigen affinity chromatography
RUO
84333
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q86SE9
PCGF5
Recombinant protein corresponding to Human PCGF5. Recombinant protein control fragment (Product #RP-97187).
100 μL
Primary
Human
Antibody
IgG
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