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Invitrogen™ PD-L1 Recombinant Rabbit Monoclonal Antibody (PD00-97)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA556521
This item is not returnable.
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Description
PD-L1 Recombinant Monoclonal Antibody for IHC (P)
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifications
| PD-L1 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q9NZQ7 | |
| Cd274 | |
| Recombinant protein with Human PD-L1 aa 19-238. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin) | |
| PD00-97 | |
| Unconjugated | |
| Cd274 | |
| A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 29126 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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